Can Vitamin C and copper cause kidney damage?

The Combined Administration of Vitamin C and Copper Induces a Systemic Oxidative Stress and Kidney Injury

Regarding this study. They claim taking Vitamin C and copper together might cause oxidative damage in kidneys. Might. Suggest. “All of these observations suggest that the combined use of AA plus Cu2+ induces renal injury.”

The Study is inapplicable to the Copper Revolution for the following reasons.

  1. They only studied rats from 5 days to 3 weeks. But it takes one full month for the body to start making many copper-dependent antioxidants, including metallothioneins and superoxide dismutase, ceruloplasmin, and others.

2A. They started the rats on 1 mg copper/kilo, which, for me, a 100 kilo man, would be 100 mg of copper. They included no adjustment period in which the body ramps up making antioxidants.

2B. There is no evidence that these researcher are even aware of the existence of copper-containing and copper-dependent antioxidants such as metallothioneins, superoxide dismutase or ceruloplasmin, (a word search for all three brought zero hits in their document) all of which would certainly mitigate and nullify their “oxidative damage” effect.

  1. They said if the rats got antioxidants, such as NAC, it would not have this effect.
  2. The amount of Vitamin C given ranged from 10,000 mg to 100,000 mg. But at normal levels, such as we take, such as 1000 mg Vitamin C, then Vitamin C is an antioxidant.
  3. There are studies showing Vitamin C at high IV levels does NOT cause kidney harm.

No Reported Renal Stones with Intravenous Vitamin C Administration: A Prospective Case Series Study

  1. They did not positively prove any kidney harm. Harm was only “suggested” through elevated proteins, and other biomarkers.
  2. We take selenium, which is another antioxidant.
  3. We take niacinamide, another antioxidant.
  4. The study was in rats, and the study results are contradicted by Vitamin C and copper in chickens:

“Intriguingly, there was also a report showing that AA at the concentration of 250 mg/kg prevented hematobiochemical alterations, oxidative stress, and kidney damage induced by 300 mg/kg CuSO4 in broiler chickens [23], which is in complete opposition to our results. The reason for the discrepancy is unclear.”

  1. We don’t take Vitamin C and copper at the same time, but we likely can, and have, with no problems. We take copper in the morning, Vitamin C in the afternoon, and zinc at night.
  1. We don’t take 100 mg of oral copper without a ramp-up period, instead we adjust, and tell others to adjust, so their bodies actually make plenty of antioxidants.
  2. We don’t gastrically lavage anyone; these experimenters were forcing these solutions into the mice, they did not let the mice drink it in their water or food as in a normal experiment. They admitted that their force feeding (the approach for administering drugs) might have been a cause of problems. Force feeding can result in a trauma injury that can show up as elevated proteins in the kidneys!

“The reason for the discrepancy is unclear. It could be due to the different experimental settings, such as indicators used for monitoring the redox state, approaches for administrating drugs, as well as species of animals used in the investigation.”

  1. We have explicitly rejected the necessity of taking a “copper-1” supplement, which is made by combining copper and Vitamin C together at the same time.
  1. We don’t subscribe to the theory of oxidative damage anyway, as oxygen is a necessary and vital nutrient. We believe in the healing power of H2O2 and oxygen therapies, which have thousands upon thousands of positive testimonials. The medical establishment also does not believe in the theory. Oxidative damage is said to be a key way that people die, and happens usually mostly when people are dying. They never give antioxidants as a therapy when oxidative damage is actually said to be taking place, to people who are dying. If they don’t believe their own lies, why should we?
  2. They were not able to kill any of the rats in the study, not even with extremely high doses of Vitamin C and copper without any adjustment period. The only rats that died were the ones they killed so they could measure the length of their colons. These experimenters are disgusting people: 1 killing rats. 2. to measure colons.
  3. The study came out in January, 2023, which was after the publication of my book, “The Copper Revolution” in January, 2022. They did not address anything in my book, and produced no information worthy of anyone’s consideration, and have contributed nothing to actual science. It was already known and established that high vitamin C acts as an oxidant, and it was already known and established that high copper, initially, without an adjustment period, acts as an oxidant, and then later, the antioxidant copper enzymes are produced. They appear to be ignorant of this process, or if they know about these things, they deliberately produced a study that might show theoretical harm in some very unusual circumstances that are inapplicable to any real life conditions.
  4. It is always important to activate your thinking capacity when reading trashy studies so as to not be mislead, deceived, or confused.


Excerpt from “The Copper Revolution” book:

Chapter 57: Nephritis, Nephrotic syndrome, and Nephrosis

Nephritis – “A condition in which the tissues in the kidney become inflamed and have problems filtering waste from the blood.”

Nephrotic syndrome / nephrosis – “kidney disease, especially when characterized by edema and the loss of protein from the plasma into the urine due to increased glomerular permeability”

Copper is an anti-inflammatory. Copper is good for the kidneys, and copper deficiency is not good for the kidneys.

Copper only becomes toxic to the kidneys in cases of suicide by copper sulfate, at doses up to 20,000 mg.

So, the key question then, is copper toxic to the kidneys at normal levels, or only at very high levels?

What about copper deficiency and kidney disease?

What does copper do for the rest of the body? What body part would not benefit from better nerves, better blood supply, and better hormone production?

Here are 5 sources saying copper deficiency is implicated in kidney disease:
“A low amount of copper could mean that you have: Kidney disease”

Selected Nutrients for Kidney Health

“Trace Elements
Decreased levels of the trace elements, copper, zinc and selenium, are often found in patients with kidney disease and those on dialysis…. kidney patients should have adequate amounts of trace minerals as delineated by the KDOQI Guidelines.”

Evaluation of serum Zinc and Copper in children with chronic kidney disease

Kids with kidney disease had the lowest copper levels, group A: “As regard Cu level it was
(89.3 ± 15.1 μg/dL) in group A,
(95.6 ± 16.2 μg/dL) in group B, while it was
(116.6 ± 13.6 μg/dL) in group C which is significantly higher than in children with CKD (p < 0.05).”

Copper deficiency in kidney patients:

11 Amazing Healing Benefits of Drinking Water in a Copper Vessel

“Copper has properties that help kill harmful bacteria and reduce inflammation within the stomach, making it a great remedy for ulcers, indigestion and infections. Copper also helps cleanse and detox your stomach, regulates the working of your liver and kidneys, and proper elimination of waste and ensures the absorption of nutrients from food.”

Which is the cause, which is the effect? Does low copper cause kidney disease, or does kidney disease cause low copper?

Many times, kidney disease is caused by diabetes. And what is diabetes caused by? Class? Anyone? That’s right. Copper deficiency!

Diabetes – A Major Risk Factor for Kidney Disease
“About 30 percent of patients with Type 1 (juvenile onset) diabetes and 10 to 40 percent of those with Type 2 (adult onset) diabetes eventually will suffer from kidney failure.”

Other causes of kidney disease:

“Diseases and conditions that cause chronic kidney disease include:

–Type 1 or type 2 diabetes
–High blood pressure
–Glomerulonephritis (gloe-mer-u-low-nuh-FRY-tis), an inflammation of the kidney’s filtering units (glomeruli)
–Interstitial nephritis (in-tur-STISH-ul nuh-FRY-tis), an inflammation of the kidney’s tubules and surrounding structures
–Polycystic kidney disease or other inherited kidney diseases
–Prolonged obstruction of the urinary tract, from conditions such as enlarged prostate, kidney stones and some cancers
–Vesicoureteral (ves-ih-koe-yoo-REE-tur-ul) reflux, a condition that causes urine to back up into your kidneys
–Recurrent kidney infection, also called pyelonephritis (pie-uh-low-nuh-FRY-tis)”

Let’s look at this list again, given what we have already established in this book:

Type 1 or type 2 diabetes — caused by copper deficiency

High blood pressure — caused by copper deficiency

Glomerulonephritis (gloe-mer-u-low-nuh-FRY-tis), an inflammation of the kidney’s filtering units (glomeruli) — inflammation is caused by copper deficiency.

Interstitial nephritis (in-tur-STISH-ul nuh-FRY-tis), an inflammation of the kidney’s tubules and surrounding structures — inflammation is caused by copper deficiency.

Polycystic kidney disease or other inherited kidney diseases — possible copper deficiency, as copper deficiency can be inherited if the mother is copper deficient.

Prolonged obstruction of the urinary tract, from conditions such as enlarged prostate, kidney stones and some cancers — caused by copper deficiency, as copper helps keep calcium in the bones, not in the soft tissues such as the kidney. Other things that help put calcium into the bones are silica, boron, magnesium, Vitamin K, and Niacin. In contrast, Vitamin D and fluoride weaken the bones.

Vesicoureteral (ves-ih-koe-yoo-REE-tur-ul) reflux, a condition that causes urine to back up into your kidneys — unknown if copper deficiency.

Recurrent kidney infection, also called pyelonephritis (pie-uh-low-nuh-FRY-tis)” — infections caused by copper deficiency.

Six out of 8 causes of kidney disease listed by the Mayo Clinic are copper deficiency symptoms!

Furthermore, kidneys are major detox organs. Copper is the major detox mineral, as copper is needed to make at least 5 detoxing enzymes.

You know what I’m about to say…

You now know more about how copper cures and prevents kidney damage than most nephrologists.


Copper, boron, and iodine all detox fluoride. Each of these minerals, if people are extra fluoride toxic, or if people scale the minerals up too fast, then occasionally people get fluoride, or other toxins, clogging up the kidneys. We have seen this on forums discussing boron and iodine. This can show up as symptoms of edema, which is swelling of the hands or feet or legs with water, or lower back pain, or kidney pain.

Solutions for this kind of temporary kidney blockage include lowering the doses of the good minerals temporarily. And then starting any basic kidney cleanse, as follows:

Kidney pain, lower back pain and/or fluid build-up/swelling. You can help detox your kidneys with 1/8th of a teaspoon of baking soda in lots of water, and/or with green smoothies. Take 1/8th of a teaspoon of baking soda per glass of water, several per day, until kidney pain is gone. This should work in about 1-2 hours. Take no more than 1 full teaspoon of baking soda per day, short term.

Leafy greens are also good for detoxing the kidneys.

Lowering salt, and increasing potassium chloride, or Nu Salt is also good for the kidneys. See: